Zahoor Ahmad Shah

TMAO at the Crossroads of the Gut–Brain Axis: Emerging Mechanisms Linking Microbiota-Derived Metabolites to Neuroinflammation and Cognitive Dysfunction

Trimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite produced through the hepatic oxidation of trimethylamine. Although TMAO has been widely investigated as a therapeutic target in multiple cardiovascular and metabolic diseases, growing evidence suggests it may pl...