Zahid Manzar

Hypertensive stretch regulates endothelial cell inflammation and apoptosis through ceramide metabolism

Hypertension and cardiovascular disease (CVD) are associated with elevated plasma levels of ceramides (Cer), a type of membrane sphingolipids (SPLs). Increased cellular Cer levels are known to cause vascular endothelial cell (EC) dysfunction. However, Cer metabolism changes due t...