Yvonne Lange

Does Complexation of Plasma Membrane Cholesterol with Phospholipids Determine its Transbilayer Distribution?

The transbilayer distribution of cholesterol in the plasma membrane is unresolved in that diverse analyses have yielded contradictory results. We now propose a model based on a novel mechanism. It assumes that (a) sterols associate stoichiometrically with phospholipids and (b) th...