Yuxuan Guo

Suppression of meiotic double-strand break formation in somatic cells by DREAM factors TCX5/6 maintains genome stability

Meiotic recombination in reproductive cells is initiated by DNA double-strand breaks (DSBs) and requires the expression of meiosis-specific genes, yet how the transcription of those genes is regulated in either meiotic or somatic cells remains unclear. Here, using a representativ...