Yutong Ge

Controllable generation of predicted non-hemolytic antimicrobial peptides by multi-guided latent diffusion

Antimicrobial peptides (AMPs) are attractive anti-infective scaffolds, but their development is often constrained by hemolysis and by the narrow physicochemical separation between bacterial killing and host-cell damage. We developed NHAMP, a protein language model (PLM)-fused lat...