Yuting Xie

The Dual-Ribozyme RNA Ladder and RNA-Calibrated ssDNA Marker System for Inexpensive RNA Size Standards

Abstract RNA size markers are essential for denaturing Urea-PAGE analysis, but commercial RNA ladders are expensive, available only in fixed size ranges, and require careful handling to prevent RNA degradation. Here, we developed a modular dual-ribozyme platform for preparing RNA...

AnEnergy-Sustainable and Oxidative-Tolerant Nanofactoryof Therapeutic Proteins for Long-Acting Therapy of Inflammatory BowelDisease

Abstract The ability to continuously generate bioactive therapeutics at the diseased site is an appealing and crucial advantage for the treatment of chronic relapsing diseases such as inflammatory bowel disease (IBD). Current in situ therapeutic factory strategies mainly rely on...