Yuting Wen

A semi-supervised deep learning framework (TBMNet) for automatic tumor budding quantification: real-world validation and clinical utility in stage II colorectal cancer

Abstract Background Tumor budding (TB) is a clinically important prognostic marker in colorectal cancer (CRC), but its assessment remains subjective and its biological basis is incompletely understood. We developed an artificial intelligence (AI)-based TB evaluation framework and...

Neuroprotection in the early window: a randomized controlled trial of butylphthalide initiation within 3 hours in acute ischemic stroke

Neuroprotective agents have shown promise in preclinical studies but failed to demonstrate efficacy in clinical trials, potentially due to delayed treatment initiation. The optimal therapeutic window for neuroprotection in acute ischemic stroke (AIS) remains undefined. We aimed t...