Yuqin Zeng

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

ABSTRACT Aberrant macrophage polarization is one of the key mechanisms underlying chronic obstructive pulmonary disease (COPD), but the underlying processes have not yet been fully elucidated. Lactylation is a novel lactate‐derived post‐translational modification and is relativel...