Yunyun Guo

ALDH2 inhibition reprograms tubular epithelial cell metabolism and promotes renal injury susceptibility

Fatty Acid Oxidation (FAO) dysfunction induces pro-fibrotic transition in tubular epithelial cells (TECs) and contributes to renal fibrosis in chronic kidney disease (CKD); however, the drivers of metabolic reprogramming in TECs remain unclear. We investigate the role of aldehyde...