Yuntong Liu

Retinoic acid maintains the primordial follicle reserve by inhibiting PI3K/Akt signaling

In female mammals, nonrenewable primordial follicles are orderly activated to maintain reproductive lifespan. However, the initiating regulator(s) of primordial follicle maintenance and activation remain poorly characterized. RA synthesis enzymes were mainly expressed in the pre-...

OGTT ‐Derived β‐Cell Function–Based Stratification of 2‐Year Glycaemic Transitions in Chinese Adults With Prediabetes

ABSTRACT Aims Prediabetes is heterogeneous, with variable progression to diabetes or reversion to normoglycemia. We evaluated whether the insulin secretion‐sensitivity index‐2 (ISSI‐2), an oral glucose tolerance test (OGTT)‐derived integrated surrogate of β‐cell function relative...