Yukun Wang

Transcriptomic and Metabolomic Analyses Reveal the Phenylpropanoid Metabolism Regulatory Network in Arabidopsis Response to Colletotrichum higginsianum Infection

Colletotrichum higginsianum (Ch) is a typical hemibiotrophic ascomycetous fungus. The diseases it causes often lead to considerable economic losses in global cruciferous crop production. However, current knowledge is still insufficient for us to gain a deeper understanding of how...

Integrated Analysis of Metabolome and Transcriptome Provides New Insights into the Genetic Basis Underlying the Regulation of α-Linolenic Acid Biosynthesis in Perilla frutescens Seeds

Perilla (Perilla frutescens) is an important oil-bearing crop rich in α-linolenic acid (ALA), and seed oil quality varies greatly among different germplasms. However, the molecular and metabolic mechanisms underlying genotypic differences in ALA accumulation remain unclear. In th...

Clinical predictors of early treatment response across systemic therapies in psoriasis: a prospective cohort study

Background Baseline clinical factors may help estimate early response in psoriasis, but real world evidence across biologics, methotrexate, and phototherapy remains limited. We used SPEECH registry data to evaluate factors associated with Physician Global Assessment (PGA) ≤ 1 at...