Yuan Zhang

Modification of Perilla (Perilla frutescens (L.) Britt.) Seed Protein via Physical Treatments for Enhanced Gelation Properties

Perilla (Perilla frutescens (L.) Britt.) seed protein, an underutilized resource derived from medicinal and edible plants, was subjected to ultrasound (400 W, 20 min), pH-shifting (pH 12.0, 1 h), and high-pressure homogenization (90 MPa, 3 cycles), applied individually or in comb...

Efficacy, safety, and pharmacokinetics of pumecitinib nasal spray for moderate-to-severe seasonal allergic rhinitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Background Seasonal allergic rhinitis (SAR) is a pollen-triggered condition causing nasal inflammation and quality of life impairment. Pumecitinib, a topical Janus kinase (JAK) inhibitor may modulate allergic inflammation. We evaluated the efficacy, safety, and pharmacokinetics o...