Yuan-Jun Gao

Chiral Phosphoric Acid-Catalyzed Asymmetric Allylic Dearomatization of Tryptamines with Alkoxyallenes

Abstract Catalytic asymmetric dearomatization of tryptamines has emerged as a powerful strategy for constructing chiral pyrroloindoline frameworks, which are ubiquitous in bioactive natural products. Despite tremendous advances in transition-metal-catalyzed synthesis of allyl-sub...