Yu Xiang

Umpolung at the meta ‐Positions of Oxazino‐Pyridines Enabling Nucleophilic Pyridine Functionalization

Selective C─H functionalization of azines is of paramount importance to synthetic and medicinal chemistry. However, nucleophilic functionalization at meta-position of pyridines has remained elusive because of the intrinsic polarity mismatch. In this study, we report a mild and pr...