Yoshinori Oie

Corneal epithelial regenerative medicine: lessons from somatic stem cell therapy toward iPS cell-based regeneration

Limbal stem cell deficiency (LSCD) is a severe ocular surface disorder caused by the loss of corneal epithelial stem cell function, and is clinically characterized by corneal neovascularization, opacity, and visual impairment. Conventional corneal transplantation for LSCD is limi...