Yoshimi Okamoto‐Uchida

YAP1 induces hepatocellular carcinoma via DNA demethylation rather than by canonical driver gene mutations

Abstract Large-scale genome sequencing analyses have identified driver gene mutations (DGMs) in most cancers as well as their associated tumorigenic mechanisms. However, a small fraction of cancers are not positive for these canonical DGMs, leaving the mechanisms underpinning the...