Yoshihisa Yamano

Divergent proviral load trajectories and clonal dynamics of HTLV-1-infected cells during antirheumatic therapy in rheumatoid arthritis

The optimal management of human T-cell leukemia virus type 1 (HTLV-1) carriers requiring long-term immunomodulatory therapy remains unclear. Patients with rheumatoid arthritis (RA) living with HTLV-1 frequently receive antirheumatic therapy, raising concerns regarding the potenti...

Quantitative Assessment of Tongue Atrophy in Amyotrophic Lateral Sclerosis Using Transoral Tongue Ultrasonography ( TOTU ): A Retrospective Single‐Center Study

INTRODUCTION/AIMS: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease accompanied by bulbar dysfunction, in which tongue atrophy contributes to dysarthria and dysphagia. Conventional tongue assessments rely on inspection, palpation, or electrophysiological testing...