Yorihisa Orita

Establishment and Characterization of OK-ATC1 and OK-ATC1-PDX: a Novel Cell Line and Patient-Derived Xenograft Model of BRAF V600E-Mutated Anaplastic Thyroid Carcinoma

Abstract Anaplastic thyroid carcinoma (ATC) is characterized by rapid progression, marked biological heterogeneity, and rarity, which makes clinical studies difficult to conduct. The development of novel therapeutic strategies for ATC thus requires appropriate experimental animal...