Yongfang Yang

Nickel-Catalyzed Strain-Release Alkyl–Alkyl Cross-Coupling of N -Chlorocyclopropamides with Tertiary α-Bromo Esters

Abstract We report a nickel-catalyzed alkyl–alkyl cross-electrophile coupling of N-chlorocyclopropamides with tertiary alkyl bromides. This method leverages cyclopropane strain release to generate alkyl radicals via β-scission of nitrogen-centered radicals, enabling efficient C(s...