Yong Qin

Mechanistic Insights into the Anti-Inflammatory Activity of a Sulfated α-Glucan (VpG) from Volutharpa ampullacea perryi

A novel sulfated α-glucan (VpG), with an ultra-high molecular weight of approximately 2250 kDa and a sulfation degree of 18.6%, was previously isolated from Volutharpa ampullacea perryi and shown to alleviate dextran sulfate sodium (DSS)-induced ulcerative colitis in mice. Howeve...

The RBMS1–SLC7A11 axis regulates ferroptosis susceptibility and lenvatinib sensitivity in hepatocellular carcinoma

Hepatocellular carcinoma remains a leading cause of cancer-related mortality worldwide. Although lenvatinib is widely deployed as a frontline systemic therapy for advanced disease, its clinical utility is frequently subverted by primary or adaptive non-responsiveness. Evasion of...