Yiyang Wu

cAMP signaling promotes acute lysosome biogenesis through TFEB nuclear import-export dynamics.

Cyclic adenosine monophosphate (cAMP) signaling is a major stimulus for lipid and glucose catabolism, yet catabolic processes like these can also coordinate with lysosome-dependent degradation. However, the impact of cAMP signaling on lysosomal dynamics remains unclear. Transcrip...