Yilun Sun

Burden and Risk Factors for Severe Respiratory Syncytial Virus Infection Among Pediatric Hematopoietic Cell Transplant Recipients

BACKGROUND: Respiratory syncytial virus (RSV) causes substantial morbidity in pediatric hematopoietic cell transplant (HCT) recipients; however, risk factors for severe disease remain incompletely characterized. METHODS: We conducted a multicenter retrospective cohort study acros...

Risk factors for Cefepime Resistance in Bacteria Causing Gram-negative Bloodstream Infections in a Children’s Cancer Center

Abstract Background Strategies that seek to provide timely and effective therapy for febrile neutropenia (FN) in children with cancer or hematopoietic cell therapy (HCT) are threatened by increasing rates of antimicrobial resistance (AR). At our institution clinically stable pati...

Patient outcomes associated with carbapenem-sparing management of febrile neutropenia

Abstract Background Febrile neutropenia (FN) guidelines recommend that local epidemiology inform empiric antibacterial treatment, but that efforts be made to restrict carbapenem administration to unstable patients. At our institution most stable patients are treated with cefepime...