Yihui Zhang

NHC-Catalyzed Asymmetric [4 + 2] Annulation of 2-Methylindole-3-Carbaldehydes to Spiro Indole-Fused Heterocycles

Abstract Indole-fused heterocyclic compounds play a crucial role in drug development. Cycloaddition reactions represent an effective strategy for the construction of such compounds. While indole derivatives often serve as C3 synthons in these reactions, there are relatively few e...