Yihan Tang

Nickel-Catalyzed β-Methyl Vinylation Using Allylamine as a Masked Alkenyl Electrophile

Abstract Direct activation of native C(sp2)–NH2 bonds in alkenyl amines remains a largely unmet challenge in cross-coupling chemistry owing to their high bond dissociation energies, poor leaving-group ability, and competing tautomerization pathways. Herein, we report a nickel-cat...