Yichen Xu

Glycosaminoglycan-Based CD44-Targeted Nanoparticles for Cancer Therapy: Biological Barriers and Barrier-Informed Design Strategies

Abstract Nanoparticle (NP)-based drug delivery has been explored to improve the therapeutic index of anticancer agents by enhancing tumor accumulation and reducing systemic toxicity. Among active targeting approaches, cluster of differentiation 44 (CD44) has attracted attention b...