Yi Long

Mitochondria–endoplasmic reticulum contacts as signaling platforms in chondrocyte homeostasis and osteoarthritis: from adaptive coupling to pathological amplification

Osteoarthritis (OA) is a progressive whole-joint disease in which cartilage degeneration remains a central pathological event. Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are prominent features of chondrocyte dysfunction, but how these processes are coordinate...