Yeun‐Mun Choo

Network Pharmacology of Natural Products from Computational Prediction to Experimental Validation

Natural products are important sources of bioactive compounds, but their complex chemical composition and multi-target effects make their mechanisms difficult to investigate using conventional approaches. Network pharmacology provides a systems-level framework for integrating che...

Phenolic Metabolites as Therapeutics for Chronic Diseases: One Researcher’s PAINS Is Another’s Translatable Polypharmacology

Abstract Phenols, natural and semisynthetic compounds in which a hydroxylated or oxygenated aromatic scaffold is a defining structural feature, occupy a paradoxical position in drug discovery. On the one hand, these compounds are frequently scrutinized for triggering Pan-Assay IN...