Ye Li

Type VI secretion system genes sciG and sciS facilitate biofilm formation of Salmonella enterica serovar Typhi

Biofilm formation is a crucial survival strategy for Salmonella enterica serovar Typhi ( S. Typhi), enabling it to withstand adverse environmental conditions and host immune responses. This process is tightly regulated by complex genetic networks. The type VI secretion system (T6...

Neuroprotection in the early window: a randomized controlled trial of butylphthalide initiation within 3 hours in acute ischemic stroke

Neuroprotective agents have shown promise in preclinical studies but failed to demonstrate efficacy in clinical trials, potentially due to delayed treatment initiation. The optimal therapeutic window for neuroprotection in acute ischemic stroke (AIS) remains undefined. We aimed t...