Yasutaka Shigemura

Pyroglutamyl peptide–rich rice protein hydrolysate restores cecal N -acetyl amino acids in high-fat-diet–fed rats, outperforming short-chain fatty acids as early microbial markers

Abstract Pyroglutamyl-leucine (pyroGlu-Leu) is a food-derived modified peptide known to modulate the gut microbiota. This study examined the effects of orally administered rice protein hydrolysate (RPH) containing pyroGlu-Leu in rats fed a 45% high-fat diet that induced mild dysb...