Yao Zeng

The long non-coding RNA FOXD2-AS1 promotes oral squamous cell carcinoma metastasis by recruiting the ADAR1-HuR complex to stabilize MYC mRNA

Abstract Metastasis remains a primary driver of poor outcomes in oral squamous cell carcinoma (OSCC), yet the underlying molecular mechanisms are incompletely understood. Here, we identify the long non-coding RNA FOXD2-AS1 as a critical regulator of OSCC metastasis through compre...

Fumarate-associated immunometabolic network in Periodontitis revealed by integrated transcriptomic and single-cell RNA sequencing analysis

Periodontitis is a long-term inflammatory disease of the gums that damages the tissues and bone supporting the teeth. Recent studies suggest that changes in cellular metabolism may influence immune responses during chronic inflammation; however, the contribution of fumarate-assoc...