Yann Guérardel

An Integrated Workflow for Real-Time Chemoenzymatic CMP-Sialic Acid Preparation and a Bioorthogonal Microplate Sialyltransferase Assay (MPSA)

Abstract Sialylation at the terminal ends of cell-surface glycoproteins and glycolipids plays a pivotal role in dictating cellular interactions, human health, and pathological processes. This crucial modification is mediated by a family of twenty distinct human sialyltransferases...