谭彦铭(Yanming Tan)

Divergent Genomic Architectures and Immune Microenvironments of BCOR-altered versus YWHAE-rearranged HGESS

High-grade endometrial stromal sarcoma (HGESS) is a rare and aggressive uterine mesenchymal neoplasm characterized by recurrent YWHAE::NUTM2 fusions and BCOR alterations. In this study, we performed integrated genomic and transcriptomic profiling of 45 HGESS and 23 low-grade endo...