Yangxiao Hou

Transcription factor ELF-1 drives inflammatory macrophage to exacerbate AKI by GBP4/NLRs/NF-κB axis

Acute kidney injury (AKI) is an unavoidable complication and critical determinant of prognosis in renal transplantation. M1-polarized macrophages are known to exacerbate AKI progression. Preliminary clinical data reveals a positive correlation between elevated E74-like ETS transc...