Yang‐Hsiang Chan

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Lateral flow assays (LFAs) are widely used for point-of-care diagnostics, but their sensitivity is often limited by inefficient antibody orientation and poor signal transduction. Herein, we report a universal strategy integrating orientation-controlled antibody conjugation at the...

Circumventing Inner Filter Effects in Ultrafast Near-Infrared II (NIR-II) Up-Conversion Spectroscopy Using Front-Face Optical Configuration

Abstract Self-absorption is fatal in up-conversion ultrafast spectroscopy, severely suppressing the fluorescent signal. To conquer this problem, we implemented a front-face optical configuration in fluorescence up-conversion spectroscopy to accurately record the intrinsic excited...