Yang Wei

Apolipoprotein A-IV deficiency rewires renal fibroblast states and intercellular communication during early obesity-associated chronic kidney disease

Abstract Aims Obesity is a major risk factor for the development and progression of chronic kidney disease (CKD). Apolipoprotein A4 (Apoa4), a key regulator of lipid and glucose metabolism, also possesses immunomodulatory properties. This study aimed to investigate the role of Ap...