Yang Hee Choi

Stem cell factor regulates endothelial HIF-2α expression during hypoxia-driven pathological angiogenesis

Hypoxia-inducible factors (HIFs) act as master regulators of hypoxia-induced pathological angiogenesis, a hallmark of various ischemic ocular diseases. Recent evidence highlights the pivotal role of HIF-2α among HIF isoforms in endothelial cells (ECs) undergoing pathological angi...