Yang Cao

Development and external validation of a machine-learning risk model for colorectal cancer triage in Sweden’s fast-track pathway

Abstract Background Fast-track colonoscopy pathways detect colorectal cancer (CRC) but strain endoscopy capacity. We developed and externally validated multivariable risk models combining faecal immunochemical test (FIT) with clinical data to triage Swedish fast-track referrals....

P1.094. Cooporation of Aldh2 Deficiency and Tp53 Loss in Alcohol-Mediated Esophageal Squamous Field Cancerization

Abstract Topic Esophageal Cancer: Esophageal Carcinogenesis Background Field cancerization in the upper aerodigestive tract is driven by alcohol, ALDH2 polymorphism, and TP53 mutation. However, animal models reflecting these factors are lacking. This study aims to clarify the com...