Yanfu Jiang

Visible-Light-Catalyzed In Situ Generation of Nitrile Oxides from Aryl Trichloromethane and TBN for [3 + 2] Cycloaddition to Access Isoxazoline/Isoxazole Scaffolds

Abstract A facile, photochemical three-component protocol for the regioselective synthesis of isoxazolines has been developed using commercially available aryl trichloromethane, alkene, and tert-butyl nitrite as starting materials. Unlike conventional methods that require presynt...