Yan-Zhong Chang

Furin deficiency in excitatory neurons leads to cognitive dysfunction and glutamatergic synaptic impairment

Furin, a pivotal member of the proprotein convertase family, exhibits markedly diminished expression in both Alzheimer’s disease (AD) patients and animal models. However, the precise mechanisms by which furin regulates AD-associated cognitive impairment have yet to be fully eluci...