Yan-Yi Chen

Cardiomyocyte-Specific LncRNA CSTPP Prolongs the Proliferation Window by Promoting CDKN1A Decay in Postinfarction Cardiac Regeneration

BACKGROUND: Adult mammalian cardiomyocytes exhibit some capacity to reenter the cell cycle after ischemic injury. However, activated cardiomyocytes rapidly undergo cell cycle rearrest shortly after activation. Long noncoding RNAs (lncRNAs) have emerged as critical regulators of c...