Yahia Hesham

Efficacy and safety of oncolytic herpes simplex virus therapy in solid tumors: a systematic review and meta-analysis of 38 clinical trials

Abstract Background Oncolytic herpes simplex virus (oHSV) therapy represents a novel immunotherapeutic approach for solid tumors. Despite regulatory approval of talimogene laherparepvec (T-VEC) for advanced melanoma, comprehensive pooled estimates of efficacy and safety across di...