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Bioorthogonal Polymer Nanozymes for Effective Treatment of Bacterial Wound Biofilm Infections

Multidrug-resistant (MDR) bacterial infections are a rapidly emerging healthcare crisis. The challenge of MDR bacteria is further exacerbated through biofilm formation that limits effective drug penetration and hinders the ability of the host immune system to clear the infection....

Polymeric nanoparticle-mediated siRNA delivery into primary human bronchial airway cells

Small interfering RNAs (siRNA) are powerful tools to target cellular protein expression, making them promising candidates for therapeutic applications. siRNA-based approaches to target detrimental mechanisms in airway diseases such as asthma and COPD are highly appealing. However...