Yacine Boulaftali

Platelet GPVI drives fibrotic lung remodeling

Platelets are a major reservoir of bioactive mediators, including growth factors such as transforming growth factor β1 (TGF-β1), that regulate vascular repair and tissue remodeling. Beyond these classical functions, platelets also participate in inflammatory hemostasis through ac...

Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia

Abstract Background Acute mesenteric ischemia (AMI) remains associated with high mortality despite prompt revascularization, suggesting that downstream ischemia–reperfusion injury contributes to poor outcomes. However, the microvascular mechanisms underlying this process are not...