Yuanwenke Zhang

Treatment response to systemic therapies in pediatric-onset versus adult-onset psoriasis: a longitudinal real-world study

Background Psoriasis may present with onset in childhood or adulthood, reflecting distinct clinical patterns. Whether treatment response differs between these groups remains unclear, particularly across systemic therapies in real-world settings.Objectives To compare longitudinal...

Clinical predictors of early treatment response across systemic therapies in psoriasis: a prospective cohort study

Background Baseline clinical factors may help estimate early response in psoriasis, but real world evidence across biologics, methotrexate, and phototherapy remains limited. We used SPEECH registry data to evaluate factors associated with Physician Global Assessment (PGA) ≤ 1 at...