Y Chen

Galectin-3 worsens microglia-mediated synaptic engulfment and neuroinflammatory responses after traumatic brain injury

Activated microglia-mediated aberrant synaptic phagocytosis is an important contributor to neurological deficits following traumatic brain injury (TBI). Galectin-3 (Gal-3), a pivotal regulator of microglial activity, is increased after TBI. However, its role in microglia-mediated...