Xuping Li

Timing of oral beta-blocker initiation and 90-day mortality in critically ill patients with acute myocardial infarction: a target trial emulation

Abstract Oral beta-blockers are used after acute myocardial infarction (AMI), but the optimal timing of initiation in critically ill patients is uncertain, and observational early-versus-late comparisons are prone to immortal-time bias. We emulated a target trial of early (≤ 24 h...