Xueying Shi

Platycladus orientalis Leaf-Derived Exosome-like Nanovesicles Delivered by Hydrogel Microneedles Restore Follicular Immune Homeostasis and Promote Hair Regeneration in Androgenetic Alopecia

Androgenetic alopecia (AGA) is the most prevalent form of hair loss, yet current therapies offer limited efficacy and fail to restore the disrupted follicular immune microenvironment. Here, we developed a bioactive hydrogel microneedle system (P-MN) in which Platycladus orientali...

Deubiquitinating Enzymes in Alzheimer’s Disease: From Protein Homeostasis to Diverse Pathological Processes

Alzheimer’s disease (AD) is a neurodegenerative disorder involving multiple pathological processes, including amyloid-β (Aβ) accumulation, tau pathology, impaired autophagy, mitochondrial dysfunction, neuroinflammation, and synaptic dysfunction. Deubiquitinating enzymes (DUBs) re...