Xudong Tang

Goblet cell heterogeneity and plasticity in ulcerative colitis: implications for mucus barrier reconstitution

The mucus barrier maintained by intestinal goblet cells is critical for colonic homeostasis, and its disruption is a key pathological hallmark of ulcerative colitis (UC). Goblet cells, once thought to be a homogeneous population of passive mucin secretors, are now recognized as a...