Xuanyuan Pan

Sleep disruption exacerbates allergic airway inflammation through sympathetic-mediated activation of the mtDNA-cGAS-STING pathway in pulmonary macrophages

Sleep disruption (SD) is increasingly recognized as a systemic stressor that worsens inflammatory disease, yet how it reshapes lung immunity remains poorly defined. To address this, we combined an ovalbumin (OVA)-induced allergic airway inflammation model with sleep disruption pa...