Xu Chen

A fitness advantage from the pLVPK plasmid fuels the global spread of a carbapenem-resistant hypervirulent Klebsiella pneumoniae high-risk clone: ST11-KL64

BACKGROUND: The global emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), particularly the ST11-KL64 subclone acquiring pLVPK-like virulence plasmids, represents a critical public health threat. This study investigates the epidemiological dominance a...

Risk factors and molecular epidemiology of ST2-type carbapenem-resistant Acinetobacter baumannii carrying blaOXA−23−like and blaOXA−51−like genes

The emergence and spread of carbapenem-resistant Acinetobacter baumannii (CRAB, A. baumannii ) has raised significant concerns and challenges globally. This study analyzes the risk factors, distribution of antibiotic resistance genes, and virulence genes associated with CRAB infe...